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.47) even further noted 3 more isoforms of human TH produced by skipping of exon three; plus they discovered increased amounts of these isoforms during the adrenal medulla of patients with progressive supranuclear palsy (PSP). We also looked for these new isoforms during the Mind, but could not detect them while in the brain of controls or patients
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As a result, and Despite the fact that D?H is necessary for noradrenaline synthesis, the amplified activity in AAAD is much more more likely to account also for the increase in noradrenaline synthesis.have already been elucidated from experiments on genetically engineered mice. Phenotypes of genetically modified mice carrying TH mutations are Prima
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